Premium type
Premio
Double Mint flavor · 105 g tube
4.5 · 468 ratings
$22.991 tube
Get the Tube on AmazonNano-hydroxyapatite toothpaste from Japan
Apagard toothpaste, one white tube in six types
Every Apagard tube looks alike until you read the small word under the name: standard, premium, stain-care. Here are all six, with what each pack says, what is inside and what a tube costs.
Meet the tubesShop Apagard on Amazon
Not sure which tube is yours? Answer three questions
- Types
- 6 tubes, one brand
- Tube size
- 100 to 135 g
- One tube from
- $19.99
The range
Apagard tubes buyers rate most
Six tubes, ordered by how many buyers have rated each. The colored arc is the one printed on the tube.
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Standard type
M-plus
Mild Mint flavor · 125 g tube
4.6 · 107 ratings
$19.991 tube
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Stain-care type
Smokin'
Mild Mint flavor · 100 g tube
4.3 · 57 ratings
$24.551 tube
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Stain-care type
Serena
Floral Mint flavor · 105 g tube
4.4 · 22 ratings
$22.991 tube
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About the brand
What Apagard is, and how to read a tube
A toothpaste built around one mineral
Apagard is a toothpaste brand from Sangi, a Tokyo company that works with hydroxyapatite. That mineral is a calcium phosphate, and it is what tooth enamel is mostly made of. Sangi puts a fine synthetic form of it into the paste and calls it nano-mHAP.
The brand has been on Japanese shelves for decades. Each tube carries the line "Made in Japan, Since 1985" on its back. The export tubes sold in the United States add English next to the Japanese, and a net weight in ounces.
What Apagard does not contain matters as much to some buyers. None of the ingredient lists names fluoride. If your dentist has told you to use a fluoride toothpaste, that advice comes first.
Side by side
The Apagard range in one table
The type is the word printed on the tube. The last column is the lowest price per tube across pack sizes.
| Line | Printed type | Flavor | Tube | One tube | Lowest per tube |
|---|---|---|---|---|---|
| Premio | Premium type | Double Mint | 105 g | $22.99 | $14.00 in 3 |
| M-plus | Standard type | Mild Mint | 125 g | $19.99 | $14.00 in 2 |
| Smokin' | Stain-care type | Mild Mint | 100 g | $24.55 | $24.55 |
| Serena | Stain-care type | Floral Mint | 105 g | $22.99 | $22.99 |
| Royal | Medical hydroxyapatite enamel restorative toothpaste | Not named | 135 g | $37.36 | $37.36 |
| Renamel | Home Care Paste | Not named | 120 g | $38.00 | $38.00 |
One design for every tube
Sangi dresses every Apagard tube the same way: white body, knurled silver cap end, a thin colored arc down one side. The arc is the code. Blue means M-plus, the standard type. Gold means Premio, the premium type.
Crimson and pink mark the two stain-care tubes, Smokin' and Serena. Royal comes in a silver carton with a black panel. Renamel wears a violet name and the words "Home Care Paste".
So the choice within the Apagard range is less about brand than about type. You pick the word under the name, then the number of tubes in the pack.
Two and three at a time
Apagard packs that lower the price per tube
Four multi-tube packs are on sale. The small figure under each price is what one tube comes to.
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Premium type
Premio, 3 tubes
Double Mint flavor · 105 g tube
4.8 · 464 ratings
$42.00$14.00 a tube
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Standard type
M-plus, 2 tubes
Mild Mint flavor · 125 g tube
4.8 · 139 ratings
$28.00$14.00 a tube
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Standard type
M-plus, 3 tubes
Mild Mint flavor · 125 g tube
4.8 · 47 ratings
$42.98$14.33 a tube
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Premium type
Premio, 2 tubes
Double Mint flavor · 100 or 105 g tube
4.8 · 47 ratings
$37.50$18.75 a tube
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What the pack claims, in Sangi's words
The English product cards keep their claims modest. For M-plus the line is "Classic formula for healthy naturally white teeth". For Premio it is "Premium care for even greater whiteness". Smokin' gets "Special formula to also remove stains (tobacco etc.)".
Those are Sangi's sentences, and they are the only promises repeated here. The cards speak of cleaning, plaque and stains. They do not carry a cavity claim, and none is added here.
Inside the tube
What an Apagard ingredient list is made of
Four jobs account for most of the list. The mineral that gives the brand its name is the fifth.
Hydroxyapatite
The calcium phosphate mineral Sangi builds the range on. Two lists print it as "hydroxyapatite (nano)".
Abrasives
Dicalcium phosphate and silica, the fine solids that do the physical cleaning under the brush.
Humectant and binder
Glycerin holds water in the paste. Cellulose gum holds the paste together on the brush.
Foam, flavor, sweetener
Sodium lauryl sulfate foams. Mint flavor and sodium saccharin set the taste. No sugar is listed.
Reading the ingredient list
Four of the tubes come with a full ingredient list in English. The lists are close cousins: a calcium phosphate abrasive, water, glycerin, silica, hydroxyapatite, a foaming agent, a binder, flavor and a sweetener.
The differences are small and easy to miss. Premio and Smokin' add PVP. Serena adds sodium metaphosphate and sodium citrate. M-plus has none of the three. Every list includes sodium lauryl sulfate, a point for anyone who avoids it.
Which tube?
Pick an Apagard tube by what you want from it
Three starting points. Each one leads to the tubes whose own packs speak to it.
An everyday tube
The standard type and the premium type, in mild mint or double mint.
Coffee, tea, wine or tobacco
The two stain-care tubes, one floral mint and one mild mint.
The tubes in Japanese cartons
Royal and Renamel, sold one at a time and priced above the rest.
On the brush
How Sangi says to use Apagard
Sangi's directions for the tube, in three moves.
- 1
A short line of paste
Put 1 to 1.5 cm of paste on the brush. That is 0.4 to 0.6 inch, less than the length of most brush heads.
- 2
Three to five minutes
Brush teeth and gums gently and with care for about 3 to 5 minutes. Sangi suggests brushing after each meal, 3 times a day.
- 3
Rinse lightly
Spit, then rinse lightly. The directions say a light rinse leaves some of the paste's hydroxyapatite behind in the mouth.
Price follows the pack, not only the type
A single tube runs from $19.99 to $38.00. The spread between types is real, but pack size moves the price per tube just as much. In packs of two and three, the cheapest tube works out at $14.00.
Royal and Renamel are sold one tube at a time. Both arrive in their Japanese cartons, with little English on the box.
Tube size is the last thing to check. An Apagard tube holds between 100 g and 135 g, depending on the type, and the net weight is printed on the carton in grams and ounces. A larger tube at the same price is the better buy, and the comparison table does that division for every pack.
None of this takes long. Read the word under the name, glance at the ingredient list if you avoid something, then decide how many tubes you want in the drawer.
Questions
Three things buyers ask first about Apagard
Does Apagard toothpaste contain fluoride?
No. None of the 5 ingredient lists shown with Apagard tubes names fluoride, and four tubes are sold as fluoride-free. The American Dental Association advises a fluoride toothpaste, so ask your dentist before switching.
What is the difference between Apagard M-plus and Premio?
M-plus is printed "standard type" and comes in a 125 g tube at $19.99. Premio is printed "premium type", comes in a 105 g tube at $22.99, and its list adds PVP.
How much does a tube of Apagard cost?
One tube costs from $19.99 to $38.00, depending on the type. In packs of 2 or 3 the lowest price per tube is $14.00.
Brand passport
Apagard in five facts
Apagard is a brand of nano-hydroxyapatite toothpaste, sold on Amazon, known for its Premio tube.
Apagard Store is an independent shop guide to Apagard toothpaste: every tube compared by the type printed on it, with ingredient lists, tube sizes and prices.
- Trademark
- APAGARD, U.S. Reg. No. 2,188,745, registered September 15, 1998 and since renewed
- Second registration
- U.S. Reg. No. 6,524,649, registered October 19, 2021, international class 5 (dental preparations)
- Lines
- Premio, M-plus, Smokin', Serena, Royal, Renamel
- Where it is sold
- On AmazonCheckout, delivery and returns happen there
- Known for
- Apagard Premio
In buyers' words
What buyers write about Apagard
Buyers in the United States, quoted in full.
Box seal arrived open
I am concerned tmof this is authentic as the seal came open and dirty (see photo) but the toothpaste is sealed. Also the tube has a made in Japan sticker on the front. I want verification this is correct packaging as i haven't ordered this one before. I use the premio or m plus.
DaKs · March 25, 2026 · Serena
So far so good.
So far so good. I can't say for 100% as yet since I'm just starting to use it. But as far as taste and how it makes my teeth feel. It's definitely not bad.
William A. · June 2, 2026 · M-plus
Expensive
I really like this stuff but it has gotten too expensive…looking at alternatives.
Ruth Smith · December 3, 2025 · Premio