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Apagard on Amazon

About the brand

About Apagard

A toothpaste brand from Tokyo, registered in the United States since 1998 and sold here in six tubes. This guide to it is independent of the company that owns it.

Apagard Premio tube lying on a pale table under a yellow flower

Brand passport

Apagard at a glance

Apagard is a brand of nano-hydroxyapatite toothpaste, sold on Amazon, known for its Premio tube.

Apagard Store is an independent shop guide to Apagard toothpaste: every tube compared by the type printed on it, with ingredient lists, tube sizes and prices.

Trademark
APAGARD, U.S. Reg. No. 2,188,745, registered September 15, 1998 and since renewedU.S. trademark register (USPTO), checked 7 October 2026
Application filed
June 7, 1996U.S. trademark register (USPTO), checked 7 October 2026
Registered for
Dentifrices, in a list of cosmetics in international class 3U.S. trademark register (USPTO), checked 7 October 2026
Home registration
The U.S. filing rests on Japanese registration No. 3079332 of October 31, 1995U.S. trademark register (USPTO), checked 7 October 2026
Second registration
U.S. Reg. No. 6,524,649, registered October 19, 2021, international class 5 (dental preparations)U.S. trademark register (USPTO), checked 7 October 2026
Trademark owner
Sangi Co., Ltd.U.S. trademark register (USPTO), checked 7 October 2026
Owner's country
JapanU.S. trademark register (USPTO), checked 7 October 2026
Lines
Premio, M-plus, Smokin', Serena, Royal, RenamelThe brand's product pages at our retail partner, checked 7 October 2026
Where it is sold
On AmazonBrand search page, read live, checked 7 October 2026
Known for
Apagard PremioBuyer rating counts, read from the product pages, checked 7 October 2026

The brand

Apagard on the record

Apagard belongs to Sangi Co., Ltd., a Japanese company. The U.S. trademark register shows the name registered for dentifrices in 1998, on the strength of a Japanese registration from 1995, and renewed since.

A second registration followed in 2021, in the class for dental preparations. Both are live, and both name the same owner.

The product itself is older than the paperwork. A 2021 review in the journal Materials credits Sangi with the first enamel restorative dentifrice, in 1978. The export tubes print "Made in Japan, Since 1985".

In the United States the Apagard lineup is six tubes. The export tubes carry English on the pack. Royal and Renamel come in their Japanese cartons.

Dates from the public record

  1. 1978

    Sangi develops its hydroxyapatite dentifrice, by the account of a 2021 review in Materials.

  2. 1995

    APAGARD is registered in Japan, No. 3079332, on October 31.

  3. 1996

    Sangi files for the U.S. trademark on June 7.

  4. 1998

    The U.S. registration issues on September 15, No. 2,188,745, covering dentifrices.

  5. 2021

    A second U.S. registration issues on October 19, No. 6,524,649, in class 5.

U.S. trademark register (USPTO), checked 7 October 2026. Materials (Basel), via PubMed Central (NIH): Chen L. et al., Hydroxyapatite in Oral Care Products: A Review (2021) read 7 October 2026

In the range

Apagard tubes buyers rate most

Who runs this

An independent shop guide

Apagard Store is an independent shop guide to Apagard toothpaste. It is not run by or affiliated with Sangi Co., Ltd, the owner of the Apagard trademark.

Apagard Store is not Sangi and does not speak for it. The guide compares the tubes, quotes what their packs say and links each one to our retail partner, where the sale takes place.

We earn a commission on purchases made through those links. It does not change the price you pay, and it does not decide which tube is called standard and which premium: the packs do that.

Questions

About the brand

Is Apagard Store the official Apagard website?

No. Apagard Store is an independent shop guide to 6 Apagard tubes. The brand's owner, Sangi Co., Ltd., runs its own websites.

Who makes Apagard toothpaste?

Sangi Co., Ltd., a Japanese company. It owns the APAGARD trademark in the United States under registration No. 2,188,745, issued in 1998.

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